1 Result for "

3047343-70-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3047343-70-1" in MCE Product Catalog:

Cat. No.: HY-158434
CAS No.: 3047343-70-1
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

IRAK1-IN-1 (compound B8) is an orally active IRAK1 inhibitor. IRAK1-IN-1 inhibits the release of IL-6 with the IC50 values of 4.57 μM and 6.51 μM on mouse cells J774A. 1 and human cells THP-1, respectively. IRAK1-IN-1 alleviats LPS (HY-D1056)-induced acute lung injury (ALI) and DSS(HY-116282C)-induced colitis in mice .
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