1 Result for "

3053689-54-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3053689-54-3" in MCE Product Catalog:

Cat. No.: HY-155356A
CAS No.: 3053689-54-3
Target:  

PROTACs Ras PERK Akt Caspase

Research Areas:  

Cancer

YN14 mixture of diastereomers is a diastereomer mixture of YN14 (HY-155356). YN14 is a KRAS G12C PROTAC degrader that recruits E3 ubiquitin ligase to induce the polyubiquitination and proteasomal degradation of KRAS G12C. YN14 induces tumor cell apoptosis, cell cycle arrest, and cell migration inhibition. YN14 exhibits in vivo antitumor proliferative activity in tumor cell xenograft nude mice. YN14 can be used in cancer-related research .
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