1 Result for "

3058199-58-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3058199-58-6" in MCE Product Catalog:

Cat. No.: HY-165607S
CAS No.: 3058199-58-6
MCB-22-174 is a deuterated Piezo1 agonist, with an EC50 value of 6.28 μM. MCB-22-174 remarkably activates the CaMKII/ERK signaling pathway and initiates Ca 2+ influx in rMSCs. MCB-22-174 significantly decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. MCB-22-174 can effectively improve bone quality in hind-limb unloading (HU) model rats. MCB-22-174 can be used for the study of disuse osteoporosis (OP) .
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