1 Result for "

3114105-24-4

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "3114105-24-4" in MCE Product Catalog:

Cat. No.: HY-175510
CAS No.: 3114105-24-4
Target:  

TREM receptor

Research Areas:  

Neurological Disease

TREM2 agonist-5 is the microglial lipid-sensing receptor (TREM2) agonist with a Kd of 71.36 μM. TREM2 agonist-5 is a racemic structural analog of the TREM2 agonist VG-3927 and exhibits superior microglial phagocytosis and activates TREM2 signaling in HEK293-hTREM2/DAP12 cells. TREM2 agonist-5 displays a superior in vitro pharmacokinetic profile to VG-3927. TREM2 agonist-5 can used for the study of Alzheimer’s disease .
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