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3115765-38-0

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Cat. No.: HY-171769
CAS No.: 3115765-38-0
Research Areas:  

Neurological Disease Cancer

dAurAB2 is a potent Aurora-A/Aurora-B PROTAC degrader with DC50 values of 59 nM and 39 nM, respectively. dAurAB2 induces ubiquitination and proteasomal degradation of Aurora-A kinase and Aurora-B kinase, and indirectly reduces N-Myc protein levels. dAurAB2 can be used in studies related to neuroblastoma .
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