1 Result for "

3125025-31-9

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "3125025-31-9" in MCE Product Catalog:

Cat. No.: HY-168895
CAS No.: 3125025-31-9
Target:  

AP-1 ERK Apoptosis

Research Areas:  

Cancer

c-Fos-IN-1 (Compound P16) is a c-Jun inhibitor, and decreases mRNA levels and protein levels of c-Fos. c-Fos-IN-1 also inhibits the phosphorylation activity of ERK and the transcriptional activity of AP-1. c-Fos-IN-1 shows anticancer activity by inhibiting ERK/c-Fos/Jun pathway. c-Fos-IN-1 inhibits the proliferation and migration of gastric cancer cells (IC50: 2.31 μM for MGC-803 cell). c-Fos-IN-1 arrests cell cycle at G2/M phase and induces cancer cell apoptosis. c-Fos-IN-1 inhibits gastric cancer tumor growth .
loading...
    loading...