1 Result for "

449733-84-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "449733-84-0" in MCE Product Catalog:

Cat. No.: HY-N6075
CAS No.: 449733-84-0
Synonyms: Nuezhenide
Specneuzhenide (Nuezhenide) is an orally active phenol glycoside isolated from Ligustrum sinense. Specneuzhenide exhibits anti-inflammatory, antioxidant, antifibrotic, antitumor, hypoglycemic, as well as cartilage- and kidney-protective activities. Specneuzhenide inhibits fibrosis by activating the AMPK pathway (Kd = 62 µM), alleviates inflammation and oxidative stress by regulating multiple signaling pathways (NF-κB, Wnt/β-catenin and HO-1/Nrf-2), and upregulates podocyte proteins to comprehensively protect renal function. Specneuzhenide can be used in research related to cancer, rheumatoid arthritis, pulmonary fibrosis, diabetic nephropathy and osteoarthritis .
loading...
    loading...