1 Result for "

485803-62-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "485803-62-1" in MCE Product Catalog:

Cat. No.: HY-P1139
CAS No.: 485803-62-1
Synonyms: PCFWKTCK
Target:  

GHSR

Research Areas:  

Metabolic Disease

Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals .
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