1 Result for "

599150-20-6

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "599150-20-6" in MCE Product Catalog:

Cat. No.: HY-107551
CAS No.: 599150-20-6
Purity:  ≥95%
Target:  

Hedgehog Gli

Research Areas:  

Cancer

Hh Pathway-IN-1, a Hedgehog (Hh) pathway inhibitor, is a potent Gli antagonist. Hh Pathway-IN-1 inhibits Hh pathway functional with an IC50 value of 1.1 µM in C3H10T1/2 cells. Hh Pathway-IN-1 does not inhibit Wnt signaling. Hh Pathway-IN-1 shows anti-proliferative activity. Hh Pathway-IN-1 decreases the GLI1 mRNA expression. Hh Pathway-IN-1 inhibits colony formation in a dose-dependent manner .
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