1 Result for "

848667-56-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "848667-56-1" in MCE Product Catalog:

Cat. No.: HY-165060
CAS No.: 848667-56-1
Synonyms: (±)2-14,15-EG
Target:  

DNA/RNA Synthesis

Research Areas:  

Metabolic Disease

(±)2-(14,15-Epoxyeicosatrienoyl) glycerol ((±)2-14,15-EG) is a novel CYP450 metabolite of 2-Arachidonoyl glycerol (2-AG) in the kidney. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol is a potent mitogen for renal epithelial cells, increasing DNA synthesis in LLCPKcl4 cells. (±)2-(14,15-Epoxyeicosatrienoyl) glycerol activates the metalloprotease ADAM17, which cleaves proTGF-α and releases TGF-α as a ligand that initiates the EGFR-ERK signalling pathway .
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