9 Results for "

873054-44-5

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "873054-44-5" in MCE Product Catalog:

30
30 Publications Verification
Cat. No.: HY-13017
CAS No.: 873054-44-5
Purity:  99.97%
Synonyms: VX-770
Target:  

CFTR Autophagy

Research Areas:  

Endocrinology

Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
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Cat. No.: HY-13017R
CAS No.: 873054-44-5
Synonyms: VX-770 (Standard)
Research Areas:  

Endocrinology

Ivacaftor (Standard) is the analytical standard of Ivacaftor. This product is intended for research and analytical applications. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
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1
1 Cited Publications
Cat. No.: HY-13017S
CAS No.: 1413431-07-8
Purity:  99.83%
Synonyms: VX-770-d9
Ivacaftor-d9 is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .
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Cat. No.: HY-13017S2
CAS No.: 1413431-05-6
Synonyms: VX-770-d18
Ivacaftor-d18 is the deuterium labeled Ivacaftor . Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively .
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Cat. No.: HY-13017S3
Purity:  ≥96.0%
Synonyms: VX-770-d4
Ivacaftor-d4 (VX-770-d4) is the deuterium labeled-Ivacaftor (HY-13017). Ivacaftor is a potent and orally active CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively .
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Cat. No.: HY-13017S1
CAS No.: 1413431-22-7
Synonyms: VX-770-d19
Ivacaftor-d9 is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research .
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Cat. No.: HY-13017S4
Synonyms: VX-770-13C6
Ivacaftor- 13C6 (VX-770- 13C6) is 13C labeled Ivacaftor. Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.
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Cat. No.: HY-13017B
CAS No.: 1134822-07-3
Synonyms: VX-770 hydrate
Target:  

CFTR Autophagy

Research Areas:  

Endocrinology

Ivacaftor hydrate (VX-770 hydrate) is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
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Cat. No.: HY-13017A
CAS No.: 1134822-09-5
Synonyms: VX-770 benzenesulfonate
Target:  

CFTR Autophagy

Research Areas:  

Endocrinology

Ivacaftor benzenesulfonate is an orally bioavailable CFTR potentiator, used for cystic fibrosis treatment.
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