1 Result for "

902434-29-1

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "902434-29-1" in MCE Product Catalog:

Cat. No.: HY-160489
CAS No.: 902434-29-1
Target:  

β-catenin Wnt

Research Areas:  

Cancer

PTK7/β-catenin-IN-2 (compound 04967) is an inhibitor of PTK7/β-catenin. It inhibits the binding of PTK7 to β-catenin (IC50: 5.6 μM), thereby inhibiting the signaling of the Wnt/β-catenin pathway. PTK7/β-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/β-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC50 of 157.1 μM .
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