1 Result for "

945260-14-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "945260-14-0" in MCE Product Catalog:

Cat. No.: HY-108263A
CAS No.: 945260-14-0
Synonyms: (S)-CGP52421
Target:  

FLT3 Drug Metabolite

Research Areas:  

Cancer

(S)-3-Hydroxy Midostaurin ((S)-CGP52421) is a potent kinases inhibitor with IC50 values of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et). (S)-3-Hydroxy Midostaurin is a minor metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (S)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML) .
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