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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
AN465
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "AN465" in MCE Product Catalog:
Cat. No.: HY-189128
CAS No.: 774546-16-6
AN-465 is a METTL3 inhibitor with an IC50 of 1.782 μM and a Kd of 8.75 μM against human METTL3. AN-465 reduces m6A modification of RNA, including EV71 2C region RNA, and disrupts the interaction between METTL3 and EV71 2C RNA. AN-465 decreases EV71-induced proinflammatory cytokine production, modulates immune cell phenotypes, alleviates EV71-induced apoptosis, restores autophagic flux, and reduces viral particle formation. AN-465 is used in the study of hand, foot and mouth disease .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
