1 Result for "

AY 9944 (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "AY 9944 (Standard)" in MCE Product Catalog:

Cat. No.: HY-107420R
CAS No.: 366-93-8
AY 9944 (Standard) is the analytical standard of AY 9944 (HY-107420). This product is intended for research and analytical applications. AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol .
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