3 Results for "

Anti-TSLP Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Anti-TSLP Antibody" in MCE Product Catalog:

Cat. No.: HY-P990535

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-TSLP Antibody is a human-derived antibody expressed in CHO cells, targeting TSLP. The Anti-TSLP Antibody contains the huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-TSLP Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P99366A
CAS No.: 1572943-04-4
Synonyms: AMG 157 (Anti-TSLP); MEDI 19929 (Anti-TSLP); Tezepelumab-ekko (Anti-TSLP)

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Tezepelumab (anti-TSLP) is human monoclonal antibody (IgG2λ) that binds specifically to TSLP, blocking it from interacting with its heterodimeric receptor. Tezepelumab can be used for the research of severe, uncontrolled asthma .
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Cat. No.: HY-P992474
TAVO101 is a humanized anti-TSLP antibody with an EC50 of 0.19 nM against hTSLP. TAVO101 inhibits STAT5 activation and CCL17 release. TAVO101 carries Fc region mutations that enhance its binding to FcRn while reducing its binding to FcγRI, FcγRIIIA and C1q, thereby attenuating effector functions. TAVO101 reduces the levels of inflammatory markers, cell infiltration and histopathological damage in preclinical models of asthma, psoriasis and atopic dermatitis. TAVO101 can be used for research related to asthma, psoriasis and atopic dermatitis .
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