1 Result for "

Antifungal agent140

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Antifungal agent140" in MCE Product Catalog:

Cat. No.: HY-179518
Target:  

Fungal PKA Ras

Research Areas:  

Infection

Antifungal agent 140 (compound 5p) is a potent antifungal agent with broad-spectrum antifungal activity. Antifungal agent 140 exerts a dual mechanism by targeting the Ras/cAMP/PKA pathway to inhibit hyphal formation and the ergosterol biosynthesis pathway. Antifungal agent 140 enhances survival, reduces fungal load in the kidneys, and strengthens host immune responses in a murine model of systemic candidiasis. Antifungal agent 140 can be used for research of resistant fungal infections .
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