2. Anti-infection Stem Cell/Wnt TGF-beta/Smad MAPK/ERK Pathway GPCR/G Protein
  3. Fungal PKA Ras
  4. Antifungal agent 140

Antifungal agent 140 (compound 5p) is a potent antifungal agent with broad-spectrum antifungal activity. Antifungal agent 140 exerts a dual mechanism by targeting the Ras/cAMP/PKA pathway to inhibit hyphal formation and the ergosterol biosynthesis pathway. Antifungal agent 140 enhances survival, reduces fungal load in the kidneys, and strengthens host immune responses in a murine model of systemic candidiasis. Antifungal agent 140 can be used for research of resistant fungal infections.

For research use only. We do not sell to patients.

Antifungal agent 140

Antifungal agent 140 Chemical Structure

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Antifungal agent 140 Related Antibodies

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Description

Antifungal agent 140 (compound 5p) is a potent antifungal agent with broad-spectrum antifungal activity. Antifungal agent 140 exerts a dual mechanism by targeting the Ras/cAMP/PKA pathway to inhibit hyphal formation and the ergosterol biosynthesis pathway. Antifungal agent 140 enhances survival, reduces fungal load in the kidneys, and strengthens host immune responses in a murine model of systemic candidiasis. Antifungal agent 140 can be used for research of resistant fungal infections[1].

Molecular Weight

520.57

Formula

C28H30F2N6O2
SMILES

FC1=C(C(CNC(CCN2CCN(C3=C4C=CC=CC4=CC=C3)CC2)=O)(O)CN5N=CN=C5)C=CC(F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Antifungal agent 140 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antifungal agent 140Antifungal agent140Antifungal agent-140FungalPKARasProtein kinase AantifungalRas/cAMP/PKAhyphal formationergosterol biosynthesissystemic candidiasisInhibitorinhibitorinhibit

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