1 Result for "

Antileishmanial agent21

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Antileishmanial agent21" in MCE Product Catalog:

Cat. No.: HY-155845
Target:  

Parasite

Research Areas:  

Infection

Antileishmanial agent-21 (compound 4e) is an antileishmanial agent that targets the Leishmania pteridine reductase 1 (Lm-PTR1). Antileishmanial agent-21 has an anti-folate mechanism, and folic acid and leucovorin can reverse the anti-leishmanial activity of Antileishmanial agent-21. Antileishmanial agent-21 inhibits the Chloroquine (HY-17589A)-resistant strain of Plasmodium falciparum (RKL9) with an IC50 of 0.0198-0.096 μM .
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