1 Result for "

Bisperoxovanadium(phen)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Bisperoxovanadium(phen)" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-122818
CAS No.: 171202-16-7
Purity:  ≥98.0%
Synonyms: Bisperoxovanadium(phen) trihydrate
BpV(phen) trihydrate, a insulin-mimetic agent, is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor with IC50s of 38 nM, 343 nM and 920 nM for PTEN, PTP-β and PTP-1B, respectively. BpV(phen) trihydrate inhibits proliferation of the protozoan parasite Leishmania in vitro. bpV(phen) trihydrate strongly induces the secretion of a large number of chemokines and pro-inflammatory cytokines, and it activates a Th1-type pathway (IL-12, IFNγ). BpV(phen) trihydrate can also induce cell apoptosis, and has anti-angiogenic and anti-tumor activity .
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