243 Results for "

CAM

" in MedChemExpress (MCE) Product Catalog:
Products (243)

243 Results for "CAM" in MCE Product Catalog:

76
76 Publications Verification
製品番号: HY-B0470
CAS 番号: 1405-10-3
Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both the nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis. Neomycin sulfate inhibits IP3-mediated Ca 2+ release, MgATP-dependent Ca 2+ uptake, and electrical excitation-evoked skeletal muscle Ca 2+ transients. Neomycin sulfate depletes gut microbiota in specific mouse models, causes hearing impairment, and kidney damage with prolonged exposure. Neomycin sulfate can be used for the research of cancer .
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37
37 Cited Publications
製品番号: HY-19805
CAS 番号: 52029-86-4
Target:  

CaMK AMPK Autophagy

研究分野:  

Metabolic Disease

STO-609 is a selective and cell-permeable inhibitor of the Ca 2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
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11
11 Cited Publications
製品番号: HY-15517B
CAS 番号: 1431698-47-3
純度:  99.99%
Target:  

CaMK

研究分野:  

Cancer

KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93 .
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11
11 Cited Publications
製品番号: HY-15517
CAS 番号: 176708-42-2
純度:  99.91%
Target:  

CaMK

研究分野:  

Cancer

KN-92 is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor .
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11
11 Cited Publications
製品番号: HY-15517A
CAS 番号: 1135280-28-2
純度:  99.68%
Target:  

CaMK Autophagy

研究分野:  

Cancer

KN-92 phosphate is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 phosphate is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 is a cell-permeable, reversible and competitive CaMKII inhibitor .
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6
6 Cited Publications
製品番号: HY-P1029
CAS 番号: 224579-74-2
Target:  

Myosin CaMK Autophagy

研究分野:  

Others

MLCK inhibitor peptide 18 is a myosin light chain kinase (MLCK) inhibitor with an IC50 of 50 nM, and inhibits CaM kinase II only at 4000-fold higher concentrations.
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5
5 Cited Publications
製品番号: HY-103319
CAS 番号: 57265-65-3
純度:  99.94%
別名: R 24571
Target:  

Autophagy Calmodulin

研究分野:  

Neurological Disease Cancer

Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively . Also in anti-cancer research . Calmidazolium binds to calmodulin with a Kd of 3 nM.
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3
3 Cited Publications
製品番号: HY-124600
CAS 番号: 1445790-55-5
純度:  99.88%
Target:  

HBV

研究分野:  

Infection

NVR 3-778 is a first-in-Class and oral bioavailable HBV CAM (capsid assembly modulator) belonging to the SBA (sulfamoylbenzamide) class, with anti-HBV activity .
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3
3 Cited Publications
製品番号: HY-P1077
CAS 番号: 145224-99-3
CALP1 is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca 2+-binding site. CALP1 blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 activates CaM-dependent phosphodiesterase activity .
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3
3 Cited Publications
製品番号: HY-P1077A
CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 µM) with binding to the CaM EF-hand/Ca 2+-binding site. CALP1 TFA blocks calcium influx and apoptosis (IC50 of 44.78 µM) through inhibition of calcium channel opening. CALP1 TFA blocks glutamate receptor channels and blocks a store-operated nonselective cation channel. CALP1 TFA activates CaM-dependent phosphodiesterase activity .
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3
3 Cited Publications
製品番号: HY-P70154
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: rHuEpithelial cell adhesion molecule/EpCAM, His; Epithelial Cell Adhesion Molecule; Ep-CAM; Adenocarcinoma-Associated Antigen; Cell Surface Glycoprotein Trop-1; Epithelial Cell Surface Antigen; Epithelial Glycoprotein; EGP; Epithelial Glycoprotein 314; EGP314; hEGP314; KSA; Tumor-Associated Calcium Signa
Species:  
Source:  
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2
2 Cited Publications
製品番号: HY-112564
CAS 番号: 1572510-42-9
純度:  99.94%
Target:  

HBV

研究分野:  

Infection

JNJ-632 is a hepatitis B virus (HBV) capsid assembly modulator (CAM).
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2
2 Cited Publications
製品番号: HY-P1075
CAS 番号: 261969-05-5
Target:  

Calcium Channel

研究分野:  

Neurological Disease Cancer

CALP3, a Ca 2+-like peptide, is a potent Ca 2+ channel blocker that activates EF hand motifs of Ca 2+-binding proteins. CALP3 can functionally mimic increased [Ca 2+]i by modulating the activity of Calmodulin (CaM), Ca 2+ channels and pumps. CALP3 has the potential in controlling apoptosis in diseases such as AIDS or neuronal loss due to ischemia .
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2
2 Cited Publications
製品番号: HY-P0271A
Target:  

CaMK

研究分野:  

Neurological Disease

Syntide 2 (TFA), a Ca 2+- and calmodulin (CaM)-dependent protein kinase II (CaMKII) substrate peptide, selectively inhibits the gibberellin (GA) response, leaving constitutive and abscisic acid-regulated events unaffected .
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2
2 Cited Publications
製品番号: HY-P82082
別名: CALM; CALM1; CALM2; CALM3; CAM; CAM1; CAM2; CAM3; CAMB; CAMC

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
製品番号: HY-P80445
別名: Alpha CAMKII; Calcium calmodulin dependent protein kinase II; Calcium/calmodulin dependent protein kinase II alpha B subunit; Calcium/calmodulin dependent protein kinase type II alpha chain; Calcium/calmodulin-dependent protein kinase (CAM kinase) II alpha; Calcium/calmodulin-dependent protein kinase II alpha; Calcium/calmodulin-dependent protein kinase II-alpha; Calcium/calmodulin-dependent protein kinase type II subunit alpha; Calcium/calmodulin-dependent protein kinase type IIA; CAM kinase II alpha chain; CAM kinase II alpha subunit; CAM kinase II subunit alpha; CAMK II alpha subunit; CAMK-II subunit alpha; CAMk2a; CAMKA; CAMKII; CAMKIINalpha; EC2.7.11.17; KCC2A_HUMAN; KIAA0968; MGC123320; MGC139375; MGC155201; mKIAA0968; PK2CDD; PKCCD; R74975; zgc:112538; zgc:123320;

Host:  

Rabbit

Application:  

WB, IP, FC, IHC-P

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
製品番号: HY-P74791
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: Neural cell adhesion molecule L1; NCAM-L1; CD171; L1CAM; CAML1; MIC5
Species:  
Source:  
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2
2 Cited Publications
製品番号: HY-P80927
別名: VCAM1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; INCAM-100; CD antigen CD106

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
製品番号: HY-124614
CAS 番号: 2133017-36-2
純度:  98.36%
Target:  

HBV

研究分野:  

Infection

GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM. GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools . GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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2
2 Cited Publications
製品番号: HY-P81271
別名: CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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