1431698-47-3
1431698-47-3
Chemical Structure
KN-92 hydrochloride
- CAS No.: 1431698-47-3
- Formula:C24H26Cl2N2O3S
- Molecular Weight:493.45
IUPAC Name: (E)-N-(2-(((3-(4-chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide hydrochloride
InChIKey: SHDNWBMPAAXAHM-IPZCTEOASA-N
SMILES: O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2CN(C/C=C/C3=CC=C(Cl)C=C3)C)=O.[H]Cl
Biological Activity: KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KN-92 hydrochloride | 99.70% | KN-92 hydrochloride is an inactive derivative of KN-93, without CaM kinase inhibitory activity. KN-92 hydrochloride is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. | ||||||||||||||||||||
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References
- [1]. Smyth JT, et al. Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism. J Biol Chem. 2002;277(38):35061-35070. [Content Brief]
- [2]. An P, et al. KN-93, a specific inhibitor of CaMKII inhibits human hepatic stellate cell proliferation in vitro. World J Gastroenterol. 2007;13(9):1445-1448. [Content Brief]
Keywords
