1 Result for "

CFI-401870

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CFI-401870" in MCE Product Catalog:

Cat. No.: HY-116190
CAS No.: 1430741-35-7
Target:  

Mps1 DNA/RNA Synthesis

Research Areas:  

Cancer

CFI-401870 is an orally active threonine tyrosine kinase (TTK (Mps1)) inhibitor with an IC50 of 3.1 nM. CFI-401870 exhibits IC50s against PLK4, KDR, AURKA and other kinases such as AURKB/INCENP were all greater than 1 μM.CFI-401870 inhibits the growth of various cancer cells, causing chromosome lag, an increase in aneuploidy and cell cycle arrest. CFI-401870 can be used for the study of cancers such as colon cancer .
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