2 Results for "

CGRP antagonist 1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CGRP antagonist 1" in MCE Product Catalog:

Cat. No.: HY-112262
CAS No.: 1123757-49-2
CGRP antagonist 1 (compound 21) is a highly potent CGRP receptor antagonist with a Ki and an IC50 of 1.7 nM and 5.7 nM, respectively .
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Cat. No.: HY-183142
CAS No.: 2252341-45-8
Target:  

CGRP Receptor

Research Areas:  

Cancer

CLR/RAMP3-receptor antagonist-1 is a selective antagonist of the CLR/RAMP3 receptor (CLR/RAMP3, AM2 receptor), with pIC50 values of 5.86, 9.21 and 9.07 against AM1 (CLR/RAMP2), AM2 (CLR/RAMP3) and CGRP (CLR/RAMP1) receptors, respectively. CLR/RAMP3-receptor antagonist-1 reduces the levels of pancreatic cancer progression markers, induces apoptosis in vitro, and prolongs survival in mouse models of pancreatic cancer. CLR/RAMP3-receptor antagonist-1 can be used in pancreatic cancer-related research .
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