2 Results for "

COX-2-IN-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "COX-2-IN-7" in MCE Product Catalog:

Cat. No.: HY-115934
Target:  

COX

Research Areas:  

Inflammation/Immunology

COX-2-IN-7 (compound 4a) is a potent, selective, and orally active inhibitor of COX-2 with an IC50 of 6.585 uM. COX-2-IN-7 has higher COX-2 selectivity than Celecoxib. COX-2-IN-7 shows good in vivo anti-inflammatory and low ulcerogenic activity .
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Cat. No.: HY-N20744
CAS No.: 10387-49-2
Synonyms: Acetylumbelliferone
7-Acetoxycoumarin (Acetylumbelliferone) is an anti-inflammatory inhibitor with antibacterial and amoebicidal activities. 7-Acetoxycoumarin reduces the phosphorylation levels of ERK, JNK, NF-κB and p38 MAPK. 7-Acetoxycoumarin downregulates the protein and mRNA expression levels of iNOS and COX-2. 7-Acetoxycoumarin inhibits the production of IL-1β, IL-6, TNF-α, NO and PG2. 7-Acetoxycoumarin reduces the degradation of IκBα. 7-Acetoxycoumarin can be used in studies related to amoebiasis and Bacillus lentus infection .
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