2. Natural Products
  3. Plants
  4. Thymelaeaceae

Thymelaeaceae

 

Thymelaeaceae (116):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-107421
    Prostratin 60857-08-1 99.80%
    Prostratin, a natural terpenoid compound, is a PKC activator, with a Ki of 12.5 nM and shows inhibitory effect on HIV-1.
    Prostratin
  • HY-N0281
    Daphnetin 486-35-1 99.77%
    Daphnetin (7,8-dihydroxycoumarin), one coumarin derivative can be found in plants of the Genus Daphne, is a potent, oral active protein kinase inhibitor, with IC50s of 7.67 μM, 9.33 μM and 25.01 μM for EGFR, PKA and PKC in vitro, respectively. Daphnetin triggers ROS-induced cell apoptosis and induces cytoprotective autophagy by modulating the AMPK/Akt/mTOR pathway. Daphnetin has anti-inflammation activitity and inhibits TNF-α, IL-1β, ROS, and MDA production. Daphnetin has schizontocidal activity against malaria parasites. Daphnetin can be used for rheumatoid arthritis , cancer and anti-malarian research.
    Daphnetin
  • HY-N0731
    Genkwanin 437-64-9 99.52%
    Genkwanin is a major non-glycosylated flavonoid with anti-flammatory activities.
    Genkwanin
  • HY-N1438
    Hydroxygenkwanin 20243-59-8 99.97%
    Hydroxygenkwanin (7-O-Methylluteolin), a natural flavonoid compound, is one of the main components of Lilac Daphne. Hydroxygenkwanin has anti-oxidant ability, anti-glioma ability and anticancer effect.
    Hydroxygenkwanin
  • HY-N2963
    Broussonin E 90902-21-9 98.11%
    Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis.
    Broussonin E
  • HY-N19835
    Isoinnovanoside 28876-18-8
    Isoinnovanoside
  • HY-N9951
    Oleodaphnone 260991-44-4
    Oleodaphnone is a natural product found in the whole plant of Daphne gracilis E. Pritz.
    Oleodaphnone
  • HY-N17386
    (Rac, Z)-Confluentin 2057429-28-2
    (Rac, Z)-Confluentin is a meroterpenoid found in the leaves and branches of Daphne genkwa. (Rac, Z)-Confluentin shows cytotoxic against cancer cells.
    (Rac, Z)-Confluentin
  • HY-N8220
    2-(2-Phenylethyl)chromone 61828-53-3 99.94%
    2-(2-Phenylethyl) chromone (Flidersiachromone) is a chromone derivative and antioxidant. 2-(2-Phenylethyl) chromone scavenges ABTS·+ free radicals, and its derivatives exhibit diverse activities including anti-inflammatory, neuroprotective, anti-tumor, and α-glucosidase inhibitory effects. 2-(2-Phenylethyl) chromone is applicable to experimental research in fields such as inflammation-related diseases, tumors, and neurodegenerative diseases.
    2-(2-Phenylethyl)chromone
  • HY-N1468
    Agarotetrol 69809-22-9 99.86%
    Agarotetrol is a chromone derivative isolated from Agarwood.
    Agarotetrol
  • HY-N0699
    Daphnoretin 2034-69-7 99.83%
    Daphnoretin (Dephnoretin; Thymelol) is a protein kinase C (PKC) activator that inhibits the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and exhibits antiviral activity. Daphnoretin exerts its antitumor effects by inhibiting the activation of the PI3K/AKT signaling pathway and triggers the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and activation of the NLRP3 inflammasome. Daphnoretin regulates the differentiation and maturation of dendritic cells, inhibits their immunostimulatory function by downregulating the phosphorylation level of JNK, and thus exerts a protective effect in skin graft rejection.
    Daphnoretin
  • HY-N7225
    Yuanhuacine 60195-70-2 99.79%
    Yuanhuacine (Gnidilatidin), a diterpene from Daphne genkwa, is an effective and highly selective inhibitor of the basal-like 2 (BL2) subtype of TNBC. Yuanhuacine can induce G2/M cell cycle arrest and has broad anti-tumor activity. Yuanhuacine is an orally active DNA damaging agent.
    Yuanhuacine
  • HY-W015616
    Benzylacetone 2550-26-7 99.78%
    Benzylacetone (4-Penylbutan-2-one) is an aromatic compound. Benzylacetone is a mushroom tyrosinase inhibitor with an IC50 of 2.8 mM, a Ki of 1.25 mM for monophenolase and an IC50 of 0.6 mM, a Ki of 0.39 mM for diphenolase. Benzylacetone inhibits free mushroom tyrosinase and enzyme-substrate complex. Benzylacetone acts as an appetite enhancer via olfactory stimulation, reduces spontaneous locomotor activity, induces weight gain. Benzylacetone exhibits repellent, fumigant, and contact toxicity against Tribolium castaneum adults.
    Benzylacetone
  • HY-N10093
    Chamaejasmine 69618-96-8 98.17%
    Chamaejasmine is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L. Chamaejasmine has antitumor activity. Chamaejasmine induces cell apoptosis, autophagy and ROS production, and activates the activity of AMPK/mTOR signal pathway.
    Chamaejasmine
  • HY-N1468R
    Agarotetrol (Standard) 69809-22-9
    Agarotetrol (Standard) is the analytical standard of Agarotetrol. This product is intended for research and analytical applications. Agarotetrol is a chromone derivative isolated from Agarwood.
    Agarotetrol (Standard)
  • HY-W097625
    6-Methoxyflavone 26964-24-9 99.73%
    6-Methoxyflavone is an orally active methoxyflavone. 6-Methoxyflavone suppresses neuroinflammation in microglia through the inhibition of TLR4/MyD88/p38 MAPK/NF-κB dependent pathways and the activation of HO-1/NQO-1 signaling. 6-Methoxyflavone induces S-phase arrest through the CCNA2/CDK2/p21CIP1 signaling pathway in HeLa cells. 6-Methoxyflavone inhibits NFAT Translocation into the nucleus and suppresses T cell activation. 6-Methoxyflavone partially restores chronic ethanol-induced behavioral deficits in mice. 6-Methoxyflavone antagonizes chronic constriction injury and diabetes associated neuropathic nociception expression. 6-Methoxyflavone can be used for the study of cancer, inflammation and neurological diseases.
    6-Methoxyflavone
  • HY-133721
    Chamaechromone 93413-00-4 99.75%
    Chamaechromone is a biflavonoid ingredient isolated from the roots of Stellera chamaejasme L. (Thymelaeaceae). Chamaechromone possesses anti-hepatitis B virus (HBV) effects against the surface antigen of HBV (HBsAg) secretion and has insecticidal activities.
    Chamaechromone
  • HY-121597
    Yuankanin 77099-20-8 99.39%
    Yuankanin is a genkwanin-5-bioside, the sugar moiety being composed of xylose and glucose. Yuankanin can be isolated from the methanol extract of the aerial parts of Gnidia involucrata (Thymelaeaceae).
    Yuankanin
  • HY-111927
    Pilloin 32174-62-2 98.98%
    Pilloin, a flavonoid isolated from Marrubium cylleneum, exerts a cytotoxic action targeted at the transformed lymphoblasts. Pilloin also possesses anti-inflammatory activity.
    Pilloin
  • HY-N12284
    6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone 84294-88-2 99.88%
    6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone (compound 12) is a chromenone.
    6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone