2. Natural Products
  3. Plants
  4. Thymelaeaceae
  5. Wikstroemia indica

Wikstroemia indica

Wikstroemia indica (11):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0699
    Daphnoretin 2034-69-7 99.83%
    Daphnoretin (Dephnoretin; Thymelol) is a protein kinase C (PKC) activator that inhibits the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and exhibits antiviral activity. Daphnoretin exerts its antitumor effects by inhibiting the activation of the PI3K/AKT signaling pathway and triggers the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and activation of the NLRP3 inflammasome. Daphnoretin regulates the differentiation and maturation of dendritic cells, inhibits their immunostimulatory function by downregulating the phosphorylation level of JNK, and thus exerts a protective effect in skin graft rejection.
    Daphnoretin
  • HY-N16760
    Wikstrol B 160963-92-8
    Wikstrol B (compound 5) is a biflavonoid microtubule/tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC50 value of 184 μM for microtubule polymerization and an EC50 of 3.02 μM against HIV-1, acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal, antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica.
    Wikstrol B
  • HY-N17063
    Triumbelletin 7-O-glucoside 2222584-03-2
    Triumbelletin 7-O-glucoside is a natural coumarin.
    Triumbelletin 7-O-glucoside
  • HY-N17168
    Stelleranol 795308-62-2
    Stelleranol is a natural flavonoid.
    Stelleranol
  • HY-N17199
    Genkwanol A 111103-90-3
    Genkwanol A is a natural flavonoid.
    Genkwanol A
  • HY-N2939
    Bis-5,5-Nortrachelogenin 870480-56-1
    Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC50 value of 48.6 mM.
    Bis-5,5-Nortrachelogenin
  • HY-N10920
    Genkwanol C 151283-11-3
    Genkwanol C, a biflavonoid, has effective antiviral activity against respiratory syncytial virus (RSV) in vitro.
    Genkwanol C
  • HY-N7287
    (+)-Matairesinol 148409-36-3
    (+)-Matairesinol is a lignan. (+)-Matairesinol has no cytotoxic activity for human pancreatic PANC-1 cancer cells.
    (+)-Matairesinol
  • HY-N3171A
    (+)-Nortrachelogenin 61521-74-2 98.68%
    (+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity.
    (+)-Nortrachelogenin
  • HY-N8910
    (7R)-Methoxy-8-epi-matairesinol 198827-23-5
    (7R)-Methoxy-8-epi-matairesinol is a Lignans product that can be isolated from the roots of Wikstroemia indica.
    (7R)-Methoxy-8-epi-matairesinol
  • HY-N0699R
    Daphnoretin (Standard) 2034-69-7
    Daphnoretin (Dephnoretin; Thymelol) (Standard) is the analytical standard of Daphnoretin (HY-N0699). This product is used for research and analytical applications. Daphnoretin is a protein kinase C (PKC) activator that can inhibit the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and has antiviral activity. Daphnoretin exerts its anti-tumor effect by inhibiting the activation of the PI3K/AKT signaling pathway, triggering the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and the activation of the NLRP3 inflammasome. Daphnoretin can regulate the differentiation and maturation of dendritic cells, by down-regulating the phosphorylation level of JNK, inhibiting its immune stimulating function, thereby playing a protective role in skin transplant rejection reactions.
    Daphnoretin (Standard)