2. Others Immunology/Inflammation PI3K/Akt/mTOR TGF-beta/Smad Anti-infection Cell Cycle/DNA Damage Epigenetics Apoptosis MAPK/ERK Pathway
  3. Akt Influenza Virus Reference Standards CDK PKC NOD-like Receptor (NLR) Bcl-2 Family HBV Caspase Apoptosis JNK PI3K
  4. Daphnoretin (Standard)

Daphnoretin (Standard)  (Synonyms: Dephnoretin (Standard); Thymelol (Standard))

Cat. No.: HY-N0699R
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Daphnoretin (Dephnoretin; Thymelol) (Standard) is the analytical standard of Daphnoretin (HY-N0699). This product is used for research and analytical applications. Daphnoretin is a protein kinase C (PKC) activator that can inhibit the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and has antiviral activity. Daphnoretin exerts its anti-tumor effect by inhibiting the activation of the PI3K/AKT signaling pathway, triggering the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and the activation of the NLRP3 inflammasome. Daphnoretin can regulate the differentiation and maturation of dendritic cells, by down-regulating the phosphorylation level of JNK, inhibiting its immune stimulating function, thereby playing a protective role in skin transplant rejection reactions.

For research use only. We do not sell to patients.

Daphnoretin (Standard)

Daphnoretin (Standard) Chemical Structure

CAS No. : 2034-69-7

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Information

Daphnoretin (Dephnoretin; Thymelol) (Standard) is the analytical standard of Daphnoretin (HY-N0699). This product is used for research and analytical applications. Daphnoretin is a protein kinase C (PKC) activator that can inhibit the expression of hepatitis B virus (HBV) surface antigen (HBsAg) and has antiviral activity. Daphnoretin exerts its anti-tumor effect by inhibiting the activation of the PI3K/AKT signaling pathway, triggering the mitochondrial apoptosis pathway. Daphnoretin alleviates chondrocyte apoptosis and inflammatory responses by inhibiting endoplasmic reticulum stress and the activation of the NLRP3 inflammasome. Daphnoretin can regulate the differentiation and maturation of dendritic cells, by down-regulating the phosphorylation level of JNK, inhibiting its immune stimulating function, thereby playing a protective role in skin transplant rejection reactions.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Molecular Weight

352.29

Formula

C19H12O7
CAS No.
SMILES

O=C1C(OC2=CC=C(C(O3)=C2)C=CC3=O)=CC4=CC(OC)=C(O)C=C4O1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Daphnoretin (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Daphnoretin (Standard)2034-69-7Dephnoretin (Standard) Thymelol (Standard)AktInfluenza VirusReference StandardsCDKPKCNOD-like Receptor (NLR)Bcl-2 FamilyHBVCaspaseApoptosisJNKPI3KPKBProtein kinase BCyclin dependent kinaseProtein kinase CHepatitis B virusc-Jun N-terminal kinasePhosphoinositide 3-kinaseInhibitorinhibitorinhibit

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