2 Results for "

CPP-115 hydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CPP-115 hydrochloride" in MCE Product Catalog:

Cat. No.: HY-W1025152
CAS No.: 760947-97-5
CPP-115 hydrochloride is an orally active, selective GABA-AT inhibitor with a Ki value of 9.7 μM. CPP-115 hydrochloride blocks GABA degradation and increases GABA levels in the brain. CPP-115 hydrochloride does not bind to GABA transporters, does not displace GABA from GABAA/GABAB receptors, and does not act as an agonist/antagonist of GABAC receptors. CPP-115 hydrochloride reduces cocaine-induced dopamine release, blocks cocaine-induced conditioned place preference, and suppresses seizure activity in a rat model of infantile spasms. CPP-115 hydrochloride can be used in research related to infantile spasms and epilepsy .
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Cat. No.: HY-116910
CAS No.: 640897-20-7
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

CPP-115 is a GABA transaminase inactivator with higher affinity and lower retinal toxicity than Vigabatrin (HY-15399). CPP-115 increases brain GABA levels by inhibiting GABA transaminase catabolism. CPP-115 can be used in the study of drug addiction and infantile spasms .
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