1 Result for "

CRX-526

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CRX-526" in MCE Product Catalog:

Cat. No.: HY-118984
CAS No.: 245515-64-4
Research Areas:  

Inflammation/Immunology

CRX-526 is a TLR4 antagonist that can block the interaction of lipopolysaccharide (LPS, HY-D1056) with the immune system, including preventing the expression of pro-inflammatory genes stimulated by LPS, as well as blocking the release of TNF-α induced by LPS. CRX-526 exhibits anti-inflammatory effects in two mouse models of colitis (namely, the dextran sodium sulfate-induced colitis model and the multidrug resistance gene 1a-deficient mouse model) .
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