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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
220 Results for "
Cancer Treatment
" in MedChemExpress (MCE) Product Catalog:
Products (220)
220 Results for "Cancer Treatment" in MCE Product Catalog:
169
169 Publications Verification
Synonyms: GSI-IX
Research Areas:
DAPT (GSI-IX) is a potent and orally active γ-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-β (Aβ) and Aβ42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment .
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69 Cited Publications
Synonyms: Sodium Valproate; VPA sodium; 2-Propylpentanoic acid sodium
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26
Target:
Pirarubicin is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
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26 Cited Publications
Synonyms: THP Hydrochloride
Target:
Pirarubicin Hydrochloride is an anthracycline antibiotics, acts as a topoisomerase II inhibitor, and is a widely used for treatment of various cancers, in particular, solid tumors.
21
21 Cited Publications
Synonyms: BB2516; TA2516
Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMPs, with potent activity against MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM) and MMP-7 (IC50=13 nM), used in the treatment of cancer. Marimastat (BB2516) is an angiogenesis and metastasis inhibitor, which limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes .
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Tasquinimod is an oral antiangiogenic agent, which has the potential for castration-resistant prostate cancer treatment. Tasquinimod binds to the regulatory Zn 2+ binding domain of HDAC4 with Kd of 10-30 nM. Tasquinimod also is a S100A9 inhibitor .
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Target:
Research Areas:
Valspodar (PSC 833) is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.
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16 Cited Publications
Cat. No.: HY-P0081
CAS No.: 579492-81-2
Synonyms: BIP-V5; BAX Inhibiting Peptide V5
Target:
Research Areas:
10
10 Cited Publications
Cat. No.: HY-P9912
CAS No.: 380610-27-5
10
10 Cited Publications
Cat. No.: HY-P9912A
CAS No.: 380610-27-5
10
10 Cited Publications
STING agonist-3, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule STING agonist with a pEC50 and pIC50 of 7.5 and 9.5, respectively. STING agonist-3 has durable anti-tumor effect and tremendous potential to improve treatment of cancer .
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10 Cited Publications
Cat. No.: HY-103665A
Purity: 98.36%
STING agonist-3 trihydrochloride, extracted from patent WO2017175147A1 (example 10), is a selective and non-nucleotide small-molecule STING agonist with a pEC50 and pEC50 of 7.5 and 9.5, respectively. STING agonist-3 trihydrochloride has durable anti-tumor effect and tremendous potential to improve treatment of cancer .
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Abemaciclib metabolite M20 (LSN3106726), the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer .
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5
5 Cited Publications
Cat. No.: HY-N1476
CAS No.: 145459-19-4
Category:
other families Pseudostellaria heterophylla (Miq.) Pax Cyclopeptides Plants Disease Research Fields Caryophyllaceae Cancer
Target:
5
5 Cited Publications
Cat. No.: HY-N0794
CAS No.: 20347-71-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
