7 Results for "

Carboxypeptidase G

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Carboxypeptidase G" in MCE Product Catalog:

Cat. No.: HY-114118S
Semaglutide-d8 is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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Cat. No.: HY-114118S1
Semaglutide-d8 tetraTFA is the deuterium labeled Semaglutide (HY-114118). Semaglutide is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing α-synuclein aggregation) and improving hepatic steatosis. Semaglutide can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer .
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Cat. No.: HY-W009602
CAS No.: 3918-87-4
Synonyms: Phe-ala
Phenylalanylalanine (Phe-ala) is an enkephalinase inhibitor and belongs to the class of dipeptides. Phenylalanylalanine inhibits dipeptidyl carboxypeptidase-mediated enkephalin degradation by cleaving the Gly3-Phe4 bond, and when co-administered with Leu-enkephalin, it produces analgesic effects with a synergistic enhancement, which can be reversed by Naloxone (HY-17417A). Phenylalanylalanine can be used in pain-related research .
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Cat. No.: HY-70003
CAS No.: 192203-60-4
Synonyms: CPG2 Inhibitor
Target:  

Carboxypeptidase

Research Areas:  

Cancer

Carboxypeptidase G2 (CPG2) Inhibitor is a novel CPG2 inhibitor with an Ki of 0.3 μM. Carboxypeptidase G2 (CPG2) Inhibitor effectively neutralizes the CPG2 activity in non-tumor sites, allowing for earlier administration of the drug and forming a complementary strategy with antibody clearance strategies. Carboxypeptidase G2 (CPG2) Inhibitor can be used for the study of antibody-directed enzyme prodrug therapy (ADEPT) .
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Cat. No.: HY-P2938
CAS No.: 9074-87-7
Synonyms: Carboxypeptidase G
Target:  

Antifolate

Research Areas:  

Cancer

Glutamate carboxypeptidase is an endo/exopeptidase targeting folate and antifolate agents. Glutamate carboxypeptidase regulates intracellular folate homeostasis by hydrolyzing γ-polyglutamate chains. Glutamate carboxypeptidase is promising for research of antifolate agents and cancers .
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Cat. No.: HY-E70958
Target:  

Carboxypeptidase

Research Areas:  

Metabolic Disease

Carboxypeptidase G, Pseudomonas sp. (EC 3.4.17.11) is a lysosomal thiol-dependent protease that stepwise cleaves γ-glutamylpteroyl polyγ-glutamic acid to generate pteroyl-α-glutamic acid (folic acid) and free glutamic acid. Carboxypeptidase G is highly specific for the γ-glutamyl bond but not for the C-terminal amino acid of the leaving group. Carboxypeptidase G can be activated by Zn 2+ ions.
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Cat. No.: HY-W009602R
CAS No.: 3918-87-4
Synonyms: Phe-ala (Standard)
Phenylalanylalanine (Standard) (Phe-ala (Standard)) is the analytical standard of Phenylalanylalanine (HY-W009602). This product is intended for research and analytical applications. Phenylalanylalanine is an enkephalinase inhibitor and belongs to the class of dipeptides. Phenylalanylalanine inhibits dipeptidyl carboxypeptidase-mediated enkephalin degradation by cleaving the Gly3-Phe4 bond, and when co-administered with Leu-enkephalin, it produces analgesic effects with a synergistic enhancement, which can be reversed by Naloxone (HY-17417A). Phenylalanylalanine can be used in pain-related research .
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