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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
Cdc42-binding kinase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "Cdc42-binding kinase" in MCE Product Catalog:
3
3 Cited Publications
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Research Areas:
BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on skin cancer by reducing substrate phosphorylation.
Cat. No.: HY-111423
CAS No.: 2226507-05-5
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BDP8900 is a potent and selective inhibitor of myotonic dystrophy-related Cdc42-binding kinases (MRCKα and MRCKβ). BDP8900 reduces substrate phosphorylation, leading to morphological changes, motility inhibition and invasiveness of cancer cells .
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(R)-BDP9066 is an isomer of BDP9066 and has lower activity compared to BDP9066. BDP9066 is a potent inhibitor of myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK). (R)-BDP9066 is derived from patent WO2019034890A1 (E118) .
Cat. No.: HY-111424AR
CAS No.: 2284549-25-1
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(R)-BDP9066 (Standard) is the analytical standard of (R)-BDP9066 (HY-111424A). This product is intended for research and analytical applications. (R)-BDP9066 is an isomer of BDP9066 and has lower activity compared to BDP9066. BDP9066 is a potent inhibitor of myotonic dystrophy Kinase-related Cdc42-binding Kinase (MRCK). (R)-BDP9066 is derived from patent WO2019034890A1 (E118) .
Cat. No.: HY-P702635
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Cdc42BPB; Cdc42-binding Protein kinase Beta; Cdc42 binding Protein kinase Beta; Cdc42BP-Beta; Myotonic Dystrophy kinase-Related Cdc42-binding kinase Beta; MRCK Beta; Serine/Threonine-Protein kinase MRCK Beta; Cdc42-binding Protein kinase Beta (DMPK-Like)
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Cat. No.: HY-P705758
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Cdc42BPB; Cdc42-binding Protein kinase Beta; Cdc42 binding Protein kinase Beta; Cdc42BP-Beta; Myotonic Dystrophy kinase-Related Cdc42-binding kinase Beta; MRCK Beta; Serine/Threonine-Protein kinase MRCK Beta; Cdc42-binding Protein kinase Beta (DMPK-Like)
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Cat. No.: HY-P701817
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Cdc42BPA; Myotonic Dystrophy kinase-Related Cdc42-binding Protein kinase Alpha; Cdc42 binding Protein kinase Alpha; Myotonic Dystrophy kinase-Related Cdc42-binding kinase Alpha; Serine/Threonine-Protein kinase MRCK Alpha; Myotonic Dystrophy kinase-Related
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Cat. No.: HY-P810947
Synonyms: KIAA0451, Cdc42BPA, Serine/threonine-protein kinase MRCK alpha, Cdc42-binding protein kinase alpha, DMPK-like alpha, Myotonic dystrophy kinase-related Cdc42-binding kinase alpha, MRCK alpha, Myotonic dystrophy protein kinase-like alpha
Cat. No.: HY-P811207
Synonyms: KIAA1124, Cdc42BPB, Serine/threonine-protein kinase MRCK beta, Cdc42-binding protein kinase beta, DMPK-like beta, Myotonic dystrophy kinase-related Cdc42-binding kinase beta, Cdc42BP-beta, MRCK beta, Myotonic dystrophy protein kinase-like beta
Cat. No.: HY-111424R
CAS No.: 2226507-04-4
Research Areas:
BDP9066 (Standard) is the analytical standard of BDP9066 (HY-111424). This product is intended for research and analytical applications. BDP9066 is a potent and selective myotonic dystrophy-related Cdc42-binding Kinase MRCK inhibitor with an IC50 of 64 nM for MRCKβ in SCC12 cells, Ki values of 0.0136 nM and 0.0233 nM for MRCKα/β in house determinations, respectively. BDP9066 has therapeutic effect on sKin cancer by reducing substrate phosphorylation.
Cat. No.: HY-P702634
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Cdc42BPG; Myotonic Dystrophy Protein kinase-Like Alpha; Cdc42 binding Protein kinase Gamma; Myotonic Dystrophy Protein kinase-Like Gamma; DMPK2; Serine/Threonine-Protein kinase MRCK Gamma; MRCKgamma; DMPK-Like Gamma; Kappa-200; MRCK Gamma; HSMDPKIN; MRCKG
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
