1 Result for "

Cks1-Skp2-Skp1 complex

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cks1-Skp2-Skp1 complex" in MCE Product Catalog:

Cat. No.: HY-P11020
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

p27 Analogue CP2 is a macrocyclic peptide inhibitor targeting the Cks1-Skp2-Skp1 complex (Kd = 32 nM). p27 Analogue CP2 blocks SCFSkp2/Cks1-mediated ubiquitylation and degradation of p27, restoring p27 levels and inhibiting cell proliferation. p27 Analogue CP2 is promising for research of cancers dependent on Skp2 overexpression such as breast cancer .
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