1 Result for "

Cx43 HC-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cx43 HC-IN-1" in MCE Product Catalog:

Cat. No.: HY-167983
CAS No.: 1840896-10-7
Target:  

Gap Junction Protein

Research Areas:  

Neurological Disease

Cx43 HC-IN-1 (Compound D4) is a selective and orally active inhibitor of connexin hemichannels (Cx43 HC). Cx43 HC-IN-1 effectively inhibits the hemichannel activity mediated by Cx43/Cx45 in denervated skeletal muscle fibers, significantly increasing the reinnervation rate of muscle fibers by neurons. Cx43 HC-IN-1 reduces neuroinflammation and neuronal overexcitation by inhibiting hemichannels in glial cells in the brain, and alleviates epilepsy in mice. Cx43 HC-IN-1 can be used for research on epilepsy and muscle diseases [1] .
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