1 Result for "

DS-PPE-GW

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "DS-PPE-GW" in MCE Product Catalog:

Cat. No.: HY-180218
Target:  

ATTECs Bcr-Abl Autophagy

Research Areas:  

Cancer

DS-PPE-GW is a BCR-ABL ATTEC degrader. DS-PPE-GW connects BCR-ABL and LC3B, thereby tethering BCR-ABL to the autophagosome membrane. DS-PPE-GW shows potent BCR-ABL degradation. DS-PPE-GW has anticancer activity against chronic myeloid leukemia (Pink: LC3B ligand (HY-10542); Blue: BCR-ABL ligand (HY-107447); Black: Linker (HY-W001860)) .
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