7 Results for "

Double bond isomers

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Double bond isomers" in MCE Product Catalog:

Cat. No.: HY-129764A
CAS No.: 211100-24-2
Synonyms: 17-trans-PGF3α
Research Areas:  

Inflammation/Immunology

(17E)-Prostaglandin F3α (17-trans-PGF3α) is a double bond isomer of Prostaglandin F3α (HY-129764) and a potential metabolite of trans dietary fatty acids. (17E)-Prostaglandin F3α has anti-inflammatory activity .
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Cat. No.: HY-W753927
CAS No.: 2420-42-0
Synonyms: C18:2(9E,12Z); C18:2 n-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

9(E),12(Z)-Octadecadienoic acid is an ω-6 polyunsaturated fatty acid and an isomer of linoleic acid (HY-N0729) that contains a trans double bond at the C9 position. It has been found as a minor component of bovine milk fat and in partially hydrogenated vegetable oils. 9(E),12(Z)-Octadecadienoic acid levels increase in rabbit meat following supplementation with heated sunflower oil, α-tocopheryl acetate, and zinc.
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Cat. No.: HY-116161
CAS No.: 130273-87-9
Target:  

Drug Intermediate

Research Areas:  

Cardiovascular Disease Others

15(R)-17-phenyl trinor Prostaglandin F2α isopropyl ester (15(R)-17-phenyl trinor PGF2α isopropyl ester) is the latanoprost-related isomer containing both a double bond at 13,14 and an inverted (β) hydroxyl group at C-15. Similar to 15(S)-latanoprost, 15(R)-17-phenyl trinor PGF2α isopropyl ester is a potential impurity in most commercial preparations of the latanoprost bulk drug product. The IC50 values for the free acid forms of 15(S)-17-phenyl trinor PGF2α and 15(R)-17-phenyl trinor PGF2α were determined to be 0.71 nM and 30 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle.1 A 3 μg dose of 15(R)-17-phenyl trinor PGF2α caused a 1.9 mmHg reduction of IOP in normotensive cynomolgus monkeys.
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Cat. No.: HY-120955
CAS No.: 57968-81-7
Research Areas:  

Others

Cloprostol, a synthetic derivative of prostaglandin F2α, is used as an ossified in veterinary medicine and the research of reproductive disorders in cattle, pigs and horses. (+)-5-trans Cloprostenol is a secondary impurity produced during the synthesis of (+) -cloprostenol .
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Cat. No.: HY-113465A
CAS No.: 75715-88-7
11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum .
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Cat. No.: HY-W747563
CAS No.: 79768-40-4
Synonyms: 11-trans LTD4
Target:  

Drug Isomer

Research Areas:  

Others

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
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Cat. No.: HY-N18338
CAS No.: 129836-86-8
Steviol-15-ene is a Δ 15-double bond isomer of steviol, a tetracyclic diterpenoid. Steviol-15-ene undergoes 7β-hydroxylation by Gibberella fujikuroi to form methyl ent-7α,13-dihydroxykaur-15-en-19-oate .
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