2 Results for "

EGFR mutant-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "EGFR mutant-IN-1" in MCE Product Catalog:

EGFR mutant-IN-1
EGFR mutant-IN-1
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Cat. No.: HY-125841
Target:  

EGFR

Research Areas:  

Cancer

EGFR mutant-IN-1, a 5-methylpyrimidopyridone derivative, is a potent and selective EGFR L858R/T790M/C797S mutant inhibitor with an IC50 of 27.5 nM, while being a significantly less potent for EGFR WT (IC50 >1.0 μM) .
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EGFR-IN-92
EGFR-IN-92
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Cat. No.: HY-161030
Target:  

EGFR

Research Areas:  

Cancer

EGFR-IN-92 (compound 15) is an allosteric T790M/L858R double mutant EGFR inhibitor. EGFR-IN-92 shows antiproliferative activity against H1975 non-small lung cancer (NSCLC) cancer cells expressing double mutant EGFR .
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