1 Result for "

EGFR-IN-57

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "EGFR-IN-57" in MCE Product Catalog:

Cat. No.: HY-146138
CAS No.: 2492382-37-1
EGFR-IN-57 (Compound 25a) is a potent, orally active EGFR-TK inhibitor with an IC50 of 0.054 µM. EGFR-IN-57 also inhibits VEGFR-2, CK2α, topoisomerase IIβ and tubulin polymerization with IC50 values of 0.087, 0.171, 0.13 and 3.61 µM, respectively. EGFR-IN-57 induces cell cycle arrest at G2/M and pre-G1 phases. EGFR-IN-57 induces cancer cell apoptosis .
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