1 Result for "

FAK-IN-16

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FAK-IN-16" in MCE Product Catalog:

Cat. No.: HY-117836
CAS No.: 1257994-15-2
Target:  

FAK

Research Areas:  

Cancer

FAK-IN-16 (compound OXA-11) is an orally active, selective focal adhesion kinase (FAK) inhibitor with an IC50 of 1.2 pM. FAK-IN-16 inhibits FAK phosphorylation at pFAK[Y397] and pFAK[Y861]. FAK-IN-16 slows tumor growth and reduces tumor vascularity, invasion. FAK-IN-16 potentiates effects of Cisplatin (HY-17394) on tumor cell proliferation and apoptosis in vitro and anti-tumor actions in mice .
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