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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
FGF21
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "FGF21" in MCE Product Catalog:
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4 Cited Publications
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TC-E 5003 is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor with an IC50 of 1.5 µM against hPRMT1. TC-E 5003 modulates the lipopolysaccharide (LPS) (HY-D1056)-induced AP-1 and NF-κB signaling pathways with anti-inflammatory properties. TC-E 5003 also upregulates the expression of Ucp1 and Fgf21, activates protein kinase A signaling and lipolysis in primary subcutaneous adipocytes from both mouse and humans. TC-E 5003 is promising for research of obesity and associated metabolic disorders, oxidative stress, inflammation and cancers .
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Cat. No.: HY-P990964
CAS No.: 2765640-39-7
Synonyms: BOS-580; LLF580
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ARI-3099 is an oral fibroblast activation protein (FAP) inhibitor. ARI-3099 specifically inhibits the proteolytic activity of FAP and blocks the cleavage of human FGF-21 between residues P171 and S172. ARI-3099 extends the half-life of circulating human FGF-21 in mice. ARI-3099 can be used in the research of type 2 diabetes and metabolic disorders .
Cat. No.: HY-174700
Human FGF21 mRNA encodes the human fibroblast growth factor 21 (FGF21) protein, a member of the fibroblast growth factor (FGF) family. FGF21 is a secreted endocrine factor that functions as a major metabolic regulator. It stimulates the uptake of glucose in adipose tissue.
Cat. No.: HY-173463
CAS No.: 925437-38-3
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Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity) and inflammatory diseases .
Cat. No.: HY-RS04898
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FGF21 Human Pre-designed siRNA Set A contains three designed siRNAs for FGF21 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16539
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Fgf21 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Fgf21 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS22971
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Fgf21 Rat Pre-designed siRNA Set A contains three designed siRNAs for Fgf21 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P72650
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF21; Fibroblast Growth Factor 21; FGF-21
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Cat. No.: HY-P700719
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: UNQ3115; PRO10196; FGF-21; FGF21
Cat. No.: HY-P705021
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: UNQ3115; PRO10196; FGF-21; FGF21
Cat. No.: HY-P70473AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FGF-21; Fibroblast Growth Factor-21(FGF-21)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
