1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. FGF Family
  4. Fibroblast Growth Factor
  5. Fibroblast Growth Factor 21 (FGF-21)

Fibroblast Growth Factor 21 (FGF-21)

Cat. No. Product Name / Synonyms Species Source
  • HY-P7345
    FGF-21 Protein, Human (CHO, His)

    rHuFGF-21, His; FGF21

    Human CHO
    FGF-21 Protein, Human (CHO, His) is a polypeptide chain containing the C-termimal His tag produced in CHO cells. FGF-21 Protein, Human (CHO, His) is a member of the fibroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.
  • HY-P78442
    FGF-21 Protein, Human (HEK293, mFc-Avi)

    UNQ3115; PRO10196; FGF-21; FGF21

    Human HEK293
    FGF-21 Proteinas, pivotal in promoting glucose uptake in adipocytes, induces SLC2A1/GLUT1 expression, not affecting SLC2A4/GLUT4, contingent on KLB. It significantly regulates systemic glucose homeostasis and insulin sensitivity, with direct KLB interaction via its C-terminus. Engagement with FGFR4 adds complexity to its molecular mechanisms, highlighting its role in orchestrating cellular responses beyond localized effects. FGF-21 Protein, Human (HEK293, mFc-Avi) is the recombinant human-derived FGF-21 protein, expressed by HEK293 , with N-mFc, N-Avi labeled tag. The total length of FGF-21 Protein, Human (HEK293, mFc-Avi) is 181 a.a., with molecular weight of 52-60 kDa.
  • HY-P7173
    FGF-21 Protein, Mouse

    rMuFGF-21; FGF21

    Mouse E. coli
    FGF-21 Protein, Mouse emerges as a metabolic hormone involved in the regulation of glucose, lipid, bile acid, and phosphate metabolism.
  • HY-P7012
    FGF-21 Protein, Human

    rHuFGF-21; Fibroblast Growth Factor-21(FGF-21)

    Human E. coli
    FGF-21 Protein, Human is an atypical member of the fibroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.
  • HY-P72651
    FGF-21 Protein, Mouse (HEK293, His)

    FGF21; Fibroblast Growth Factor 21; FGF-21

    Mouse HEK293
    FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGF-21 Protein, Mouse (HEK293, His) is 182 a.a., with molecular weight of 20-29 kDa.
  • HY-P701092
    FGF-21 Protein, Human (181aa)

    rHuFGF-21; Fibroblast Growth Factor-21(FGF-21)

    Human E. coli
    FGF-21 Protein, Human is an atypical member of the fibroblast growth factor (FGF) subfamily, acts as a metabolic regulator with pleiotropic effects.
  • HY-P70473
    FGF-21 Protein, Human (His)

    Fibroblast Growth Factor 21; FGF-21; FGF21

    Human E. coli
    FGF-21 Proteinas influences glucose uptake in adipocytes by inducing SLC2A1/GLUT1 expression, particularly with KLB's presence. It plays a crucial role in systemic glucose homeostasis and insulin sensitivity, interacting directly with KLB through its C-terminus and engaging with FGFR4. The protein's molecular mechanisms involve a complex interplay, emphasizing its broad impact beyond localized effects. FGF-21 Protein, Human (His) is the recombinant human-derived FGF-21 protein, expressed by E. coli , with N-6*His labeled tag. The total length of FGF-21 Protein, Human (His) is 181 a.a., with molecular weight of ~23.0 kDa.
  • HY-P72650
    FGF-21 Protein, Cynomolgus (HEK293, His)

    FGF21; Fibroblast Growth Factor 21; FGF-21

    Cynomolgus HEK293
    FGF-21 is a metabolic regulator and a potential anti-diabetic agent. FGF-21 regulates energy balance and glucose and lipid homeostasis through a heterodimeric receptor complex comprising FGFR1 and 尾-klotho. FGF-21 can also signal through FGFR2 and FGFR3. FGF-21 can be used for research of obesity, NASH, NAFLD, and type 2 diabetes mellitus. FGF-21 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived FGF-21 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of FGF-21 Protein, Cynomolgus (HEK293, His) is 181 a.a., with molecular weight of 19-24 kDa.
  • HY-P75762
    FGF-21 Protein, Hamster (HEK293, His)

    FGF21; Fibroblast Growth Factor 21; FGF-21

    Others HEK293
    FGF21 is a liver factor that signals through the FGF21 receptor in the paraventricular nucleus of the hypothalamus to regulate monosaccharide intake and preference for sweets. FGF21 promotes the progression of non-small cell lung cancer by activating the SIRT1/PI3K/AKT signaling pathway. FGF21 plays an important role in embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 Protein, Hamster (HEK293, His) is the recombinant FGF-21 protein, expressed by HEK293 , with C-His labeled tag. The total length of FGF-21 Protein, Hamster (HEK293, His) is 209 a.a., with molecular weight of ~21.16 kDa.
  • HY-P70473AF
    Animal-Free FGF-21 Protein, Human (His)

    FGF-21; Fibroblast Growth Factor-21(FGF-21)

    Human E. coli
    FGF-21 Proteinas, pivotal in promoting glucose uptake in adipocytes, induces SLC2A1/GLUT1 expression, not affecting SLC2A4/GLUT4, contingent on KLB. It significantly regulates systemic glucose homeostasis and insulin sensitivity, with direct KLB interaction via its C-terminus. Engagement with FGFR4 adds complexity to its molecular mechanisms, highlighting its role in orchestrating cellular responses beyond localized effects. Animal-Free FGF-21 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-21 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free FGF-21 Protein, Human (His) is 181 a.a., with molecular weight of ~20.35 kDa.
  • HY-P700719
    FGF-21 Protein, Human (Biotinylated, HEK293, mFc-Avi)

    UNQ3115; PRO10196; FGF-21; FGF21

    Human HEK293
    FGF-21 Proteinas, pivotal in promoting glucose uptake in adipocytes, induces SLC2A1/GLUT1 expression, not affecting SLC2A4/GLUT4, contingent on KLB. It significantly regulates systemic glucose homeostasis and insulin sensitivity, with direct KLB interaction via its C-terminus. Engagement with FGFR4 adds complexity to its molecular mechanisms, highlighting its role in orchestrating cellular responses beyond localized effects. FGF-21 Protein, Human (Biotinylated, HEK293, mFc-Avi) is the recombinant human-derived FGF-21 protein, expressed by HEK293 , with N-Avi, N-mFc labeled tag. The total length of FGF-21 Protein, Human (Biotinylated, HEK293, mFc-Avi) is 181 a.a., with molecular weight of 55-65 kDa.
Cat. No. Product Name Effect Purity