Fas receptor

By Targets:	Apoptosis (8) Bcl-2 Family (2) Caspase (3) Fatty Acid Synthase (FASN) (3) GLUT (2) Interleukin Related (1) JNK (1) MicroRNA (2) mRNA (1) NF-κB (1) NOD-like Receptor (NLR) (1) PERK (1) Reference Standards (3) RIP kinase (1) TNF Receptor (3) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (7) Cardiovascular Disease (3) Inflammation/Immunology (2) Metabolic Disease (2) Neurological Disease (1)
Oligonucleotides:	mRNA (1)

Targets Recommended: FASTK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-103243

TCPOBOP 4 Publications Verification	Bcl-2 Family	Cancer
TCPOBOP is a *constitutive androstane receptor* (CAR)** agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss . TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins .

HY-P10102

Kp7-6 2 Publications Verification	Apoptosis PERK NF-κB Caspase JNK	Inflammation/Immunology Cancer
Kp7-6 is a *Fas* mimetic peptide and also a *Fas/FasL* antagonist. Kp7-6 specifically binds to *Fas* and FasL, disrupts receptor complexes, and blocks downstream apoptosis signaling pathways. Kp7-6 inhibits the phosphorylation of ERK1-2, induces the phosphorylation of IκBα, and activates NF-κB. Kp7-6 inhibits the activation of caspase-8, caspase-3 and JNK, and suppresses human amylin-induced β-cell apoptosis. Kp7-6 inhibits FasL-induced lymphoid cytotoxicity and apoptosis. Kp7-6 reduces local tumor FasL expression, increases CD8 ⁺Fas ⁺ T cell infiltration, and decreases tumor volume in pancreatic neuroendocrine tumor models. Kp7-6 prevents concanavalin A-induced liver injury in mice. Kp7-6 is applicable to research related to type 2 diabetes, concanavalin A-induced hepatitis and pancreatic neuroendocrine tumors .

HY-101849

Fasentin 4 Publications Verification	GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC₅₀=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

HY-N0686

Pseudoprotodioscin 1 Publications Verification	Fatty Acid Synthase (FASN) MicroRNA	Metabolic Disease
Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides .

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN) Apoptosis Interleukin Related Toll-like Receptor (TLR) NOD-like Receptor (NLR) Caspase	Neurological Disease
Xelafaslatide (ONL-1204) is a *Fas* receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma .

HY-P6440

Met-12	Apoptosis Caspase	Others
Met-12 is a small peptide inhibitor of the **Fas receptor. Met-12 can inhibit Fas receptor**-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor .

HY-108610C

(S)-Edelfosine (S)-ET-18-OCH3	Apoptosis	Cancer
(S)-Edelfosine ((S)-ET-18-OCH3) is the (S)-enantiomer of Edelfosine (ET-18-OCH3) (HY-108610C). Edelfosine is a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 Death receptor .

HY-146197

Apoptotic agent-1	Apoptosis	Cancer
Apoptotic agent-1 (Compound 8a) is an apoptotic agent with high antiproliferative activity against cancer cells and low cytotoxic effect. Apoptotic agent-1 induces over-expression of Fas receptor and Cyto C genes .

HY-101849R

Fasentin (Standard)	Reference Standards GLUT TNF Receptor Apoptosis	Cardiovascular Disease Cancer
Fasentin (Standard) is the analytical standard of Fasentin. This product is intended for research and analytical applications. Fasentin, a potent glucose uptake inhibitor, inhibits GLUT-1/GLUT-4 transporters. Fasentin preferentially inhibits GLUT4 (IC50=68 μM) over GLUT1. Fasentin is a death receptor stimuli (FAS) sensitizer and sensitizes cells to FAS-induced cell death. Fasentin is also a tumor necrosis factor (TNF) apoptosis-inducing ligand sensitizer. Fasentin blocks glucose uptake in cancer cell lines and has anti-angiogenic activity .

HY-103243R

TCPOBOP (Standard)	Reference Standards Bcl-2 Family	Cancer
TCPOBOP (Standard) is the analytical standard of TCPOBOP. This product is intended for research and analytical applications. TCPOBOP is a constitutive androstane receptor (CAR) agonist that induces robust hepatocyte proliferation and hepatomegaly without any liver injury or tissue loss . TCPOBOP attenuates Fas-induced murine liver injury by altering Bcl-2 proteins .

HY-N0686R

Pseudoprotodioscin (Standard)	Reference Standards Fatty Acid Synthase (FASN) MicroRNA	Metabolic Disease
Pseudoprotodioscin (Standard) is the analytical standard of Pseudoprotodioscin. This product is intended for research and analytical applications. Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides .

HY-168770

Cl-Necrostatin-1	RIP kinase TNF Receptor Apoptosis	Cardiovascular Disease
Cl-Necrostatin-1 is a RIPK1 inhibitor. Cl-Necrostatin-1 can also inhibit TNF-α-induced necroptosis in Jurkat cells deficient in Fas-associated death domain protein (FADD; EC₅₀ = 180 nM), a modification that prevents caspase activation in response to death-domain receptor signaling. Cl-Necrostatin-1 can also reduce infarct size in a mouse model of middle cerebral artery occlusion (MCAO). Cl-Necrostatin-1 is used for research in cardiovascular and cerebrovascular diseases .

HY-174714

Human FAS mRNA	mRNA	Inflammation/Immunology
Human FAS mRNA encodes the human Fas cell surface death receptor (FAS) protein, a member of the TNF-receptor superfamily. FAS has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.

Cat. No.	Product Name	Target	Research Area

HY-P10102

Kp7-6 2 Publications Verification	Apoptosis PERK NF-κB Caspase JNK	Inflammation/Immunology Cancer
Kp7-6 is a *Fas* mimetic peptide and also a *Fas/FasL* antagonist. Kp7-6 specifically binds to *Fas* and FasL, disrupts receptor complexes, and blocks downstream apoptosis signaling pathways. Kp7-6 inhibits the phosphorylation of ERK1-2, induces the phosphorylation of IκBα, and activates NF-κB. Kp7-6 inhibits the activation of caspase-8, caspase-3 and JNK, and suppresses human amylin-induced β-cell apoptosis. Kp7-6 inhibits FasL-induced lymphoid cytotoxicity and apoptosis. Kp7-6 reduces local tumor FasL expression, increases CD8 ⁺Fas ⁺ T cell infiltration, and decreases tumor volume in pancreatic neuroendocrine tumor models. Kp7-6 prevents concanavalin A-induced liver injury in mice. Kp7-6 is applicable to research related to type 2 diabetes, concanavalin A-induced hepatitis and pancreatic neuroendocrine tumors .

HY-P10227

Xelafaslatide ONL-1204	Fatty Acid Synthase (FASN) Apoptosis Interleukin Related Toll-like Receptor (TLR) NOD-like Receptor (NLR) Caspase	Neurological Disease
Xelafaslatide (ONL-1204) is a *Fas* receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma .

HY-P6440

Met-12	Apoptosis Caspase	Others
Met-12 is a small peptide inhibitor of the **Fas receptor. Met-12 can inhibit Fas receptor**-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0686

Pseudoprotodioscin 1 Publications Verification	Structural Classification Classification of Application Fields Dioscorea nipponica Makino Metabolic Disease Plants Disease Research Fields Steroids Dioscoreaceae Source Classification	Fatty Acid Synthase (FASN) MicroRNA
Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides .

HY-N0686R

Pseudoprotodioscin (Standard)	Structural Classification Natural Products Dioscorea nipponica Makino Plants Dioscoreaceae Source Classification	Reference Standards Fatty Acid Synthase (FASN) MicroRNA
Pseudoprotodioscin (Standard) is the analytical standard of Pseudoprotodioscin. This product is intended for research and analytical applications. Pseudoprotodioscin, a furostanoside, inhibits SREBP1/2 and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides .

Species:	Human (9) Rat (2) Mouse (3) Cynomolgus (2)
Tag:	His (7) Tag Free (3) Avi (2) GST (1) Fc (5)
Source:	HEK293 (13) Sf9 insect cells (1) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P7169

	Fas/CD95 Protein, Human rHuFasR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; Fas1; Apo-1	Human	E. coli
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human has a full length of 157 amino acids (R17-N173), produced in E.coli with tag free.

HY-P7168

	Fas/CD95 Protein, Human (HEK293) rHuFasR/TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Fas receptor; CD95; APT1; Fas1; Apo-1	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293) has a full length of 157 amino acids (Q26-S172), produced in HEK293 cells with tag free.

HY-P70329

	Fas/CD95 Protein, Human (HEK293, His) rHuTumor necrosis factor receptor superfamily member 6/TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; APT1; Fas1; TNFRSF6 and Fas	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, His) has a full length of 147 amino acids (Q26-N173), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P78296

	Fas/CD95 Protein, Mouse (HEK293, Fc) FasLG receptor; CD95; APT1; Fas1; TNFRSF6; Fas; ALPS1A; APO1; FasTM; FasR	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, Fc) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal hFc-tag.

HY-P76330

	Fas/CD95 Protein, Cynomolgus (HEK293) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293) has a full length of 173 amino acids (M1-D173), produced in HEK293 cells with tag free.

HY-P70330

	Fas/CD95 Protein, Mouse (HEK293, His) rMuTumor necrosis factor receptor superfamily member 6//TNFRSF6, His; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; CD95; Fas; TNFRSF6	Mouse	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Mouse Fas receptor contain a death domain (222-306 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Mouse (HEK293, His) has a full length of 148 amino acids (Q22-R169), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P73049

	Fas/CD95 Protein, Rat (HEK293, His) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, His) has a full length of 149 amino acids (Q22-K170), produced in HEK293 cells with C-terminal 6*His-tag.

HY-P73047

	Fas/CD95 Protein, Human (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Human	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Human Fas receptor contain a death domain (230-314 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Human (HEK293, Fc) has a full length of 173 amino acids (M1-N173), produced in HEK293 cells with C-terminal hFc-tag.

HY-P73048

	Fas/CD95 Protein, Rat (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Rat	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Rat Fas receptor contain a death domain (219-303 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Rat (HEK293, Fc) produced in HEK293 cells with C-terminal hFc tag.

HY-P76331

	Fas/CD95 Protein, Cynomolgus (HEK293, Fc) Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; CD95; Fas; APT1; Fas1; TNFRSF6	Cynomolgus	HEK293
	Fas receptor is a cell surface death receptor, can bind to Fas ligand to form death-inducing signaling complexes, such as Fas associated death domain proteins (FADD). Fas receptor participates in the caspase cascade and regulate the activation of JNK and p38-K downstream. It is also involved in the signaling cascade of ERK/JNK MAPKs, activating MAPK3/ERK1, MAPK8/JNK and NF-κB, which has been implicated in the pathogenesis of various malignant tumors and immune system diseases. Macaca mulatta Fas receptor contain a death domain (228-312 a.a.) that plays a key role in regulating programmed death. Fas/CD95 Protein, Cynomolgus (HEK293, Fc) is produced in HEK293 cells with C-terminal hFc-tag.

HY-P77364

	FCMR/FAIM3 Protein, Human (HEK293, Fc) Fas apoptotic inhibitory molecule 3; IgM Fc fragment receptor; FCMR; FAIM3; TOSO	Human	HEK293
	The FCMR/FAIM3 protein plays a critical role in immune system processes and uniquely protects against FAS, TNF alpha, and FADD-induced apoptosis. Unlike traditional apoptosis inhibitors, FCMR/FAIM3 activates the inhibitory pathway and prevents CASP8 activation after FAS stimulation. FCMR/FAIM3 Protein, Human (HEK293, Fc) is the recombinant human-derived FCMR/FAIM3 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FCMR/FAIM3 Protein, Human (HEK293, Fc) is 234 a.a., with molecular weight of ~66 kDa.

HY-P79135

	Stabilin-2 Protein, Human (His) Stabilin-2; STAB2; Fas1 EGF-like and X-link domain-containing adhesion molecule 2; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL-2; Hyaluronan receptor for endocytosis; FEEL2; FELL; FEX2; HARE	Human	E. coli
	Stabilin-2 protein is a multifunctional phosphatidylserine and hyaluronic acid receptor that engulfs apoptotic cells and mediates hyaluronic acid endocytosis. As a systemic scavenger receptor, it binds various ligands and supports extracellular matrix turnover and body mobility. Stabilin-2 Protein, Human (His) is the recombinant human-derived Stabilin-2 protein, expressed by E. coli , with C-His labeled tag.

HY-P78363

	TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Mouse	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and activates apoptosis through FADD-mediated recruitment of caspase-8 to form death-inducing signaling complex (DISC).It initiates caspase cascade-mediated apoptosis and promotes NF-kappa-B activation, which is critical for ER stress-induced apoptosis.TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) TRAIL R2/TNFRSF10B Protein, Mouse (HEK293, His) is the recombinant mouse-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-His labeled tag.

HY-P78530

	TRAIL R2/TNFRSF10B Protein, Human (HEK293, His-Avi) CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Human	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and recruits caspase-8 through FADD to initiate cell apoptosis. It forms the death-inducing signaling complex (DISC), activates caspases and mediates apoptosis. TRAIL R2/TNFRSF10B Protein, Human (HEK293, His-Avi) is the recombinant human-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P701698

	HIPK3 Protein, Human (Active, sf9, GST) HIPK3; Homeodomain-interacting protein kinase 3; Androgen receptor-interacting nuclear protein kinase; ANPK; Fas-interacting serine/threonine-protein kinase; FIST; Homolog of protein kinase YAK1	Human	Sf9 insect cells
	HIPK3 is a multifaceted serine/threonine protein kinase that plays multiple roles in transcriptional regulation, apoptosis, and steroidogenic gene expression. It phosphorylates the transcription factors JUN and RUNX2, contributing to complex gene expression control. HIPK3 Protein, Human (sf9, GST) is the recombinant human-derived HIPK3 protein, expressed by sf9 insect cells , with N-GST labeled tag.

HY-P78220

	TRAIL R2/TNFRSF10B Protein, Human (Biotinylated, HEK293, His-Avi) CD262; DR5; DR5TRICK2B; Fas-like protein; KILLER/DR5; TNFRSF10B; TRAIL R2; TRAIL receptor 2; TRAILR2; TRICK2; TRICK2A; TRICKB; ZTNFR9; KILLER	Human	HEK293
	TRAIL R2/TNFRSF10B protein is the receptor of TNFSF10/TRAIL and recruits caspase-8 through FADD to initiate cell apoptosis. It forms the death-inducing signaling complex (DISC), activates caspases and mediates apoptosis. TRAIL R2/TNFRSF10B Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TRAIL R2/TNFRSF10B protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

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Host:	Mouse (6) Rabbit (1)
Reactivity:	Human (7) Mouse (3)
Application:	IHC-P (1) ICC/IF (5) IP (1) WB (6) FC (1) ELISA (3)
Isotype:	IgG (1) IgG1 (3) IgG2a (1)
Conjugation:	Non-conjugated (7) Biotin (1)
Clonality:	Monoclonal (5)
Modification:	Unmodified (5)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86549

	Fas Antibody (YA6241) Fas; APT1; Fas1; TNFRSF6; Tumor necrosis factor receptor superfamily member 6; Apo-1 antigen; Apoptosis-mediating surface antigen Fas; FasLG receptor; CD antigen CD95	WB, IHC-P, ICC/IF, IP, ELISA	Human
	Fas Antibody (YA6241) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Fas.

HY-P85515

	Fas(C-term) Antibody (YA5207) ALPS 1A; ALPS1A; APO 1; Apo 1 antigen; APO 1 cell surface antigen; Apo-1 antigen; APO1; Apo1 antigen; APO1 cell surface antigen; Apoptosis antigen 1; Apoptosis mediating surface antigen Fas; Apoptosis-mediating surface antigen Fas; APT 1; APT1; CD 95; CD 95 antigen; CD95; CD95 antigen; Delta Fas; Delta Fas/APO 1/CD95; Delta Fas/APO1/CD95; Fas; TNF receptor superfamily, member 6; Fas 1; Fas 827dupA; Fas AMA; Fas; Fas Antigen; Fas cell surface death receptor; Fas1; FasLG receptor; FasTM; sFas; Surface antigen APO1; TNF receptor superfamily, member 6; TNFRSF 6; TNFRSF6; TNR6_HUMAN; Tumor necrosis factor receptor superfamily member 6.	WB	Human
	Fas(C-term) Antibody (YA5207) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fas(C-term).

HY-P85636

	FADD Antibody (YA5328) FADD; FADD protein; FADD_HUMAN; Fas; TNFRSF6; associated via death domain; Fas associated via death domain; Fas associating death domain containing protein; Fas associating death domain containing protein; Fas associating protein; Fas associating protein with death domain; Fas associating protein with death domain; Fas TNFRSF6 associated via death domain; Fas-associated death domain protein; Fas-associating death domain-containing protein; FasTNFRSF6 associated via death domain; FasTNFRSF6 associated via death domain; GIG 3; GIG3; Growth inhibiting gene 3 protein; Growth-inhibiting gene 3 protein; H sapiens mRNA for mediator of receptor induced toxicity; H sapiens mRNA for mediator of receptor induced toxicity; Mediator of receptor induced toxicity; Mediator of receptor induced toxicity; MGC8528; MGC8528; MORT 1; MORT1; MORT1; Protein FADD.	WB, ICC/IF, ELISA	Human
	FADD Antibody (YA5328) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FADD.

HY-P87407A

	TNFRSF6B/DcR3 Antibody (YA7095)(PBS only) DCR3, TR6, UNQ186/PRO212, TNFRSF6B, Tumor necrosis factor receptor superfamily member 6B, Decoy receptor 3, Decoy receptor for Fas ligand, M68, DcR3	FC, ELISA	Human
	TNFRSF6B/DcR3 Antibody (YA7095) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TNFRSF6B/DcR3.

HY-P80916

	DR5 Antibody (YA660) Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; D	WB, ICC/IF	Human, Mouse
	DR5 Antibody (YA660) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DR5.

HY-P80916A

	DR5 Antibody (YA660)(PBS only) Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; D	WB, ICC/IF	Human, Mouse
	DR5 Antibody (YA660) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DR5.

HY-P85577

	DR5 Antibody (YA5269) Fas like protein; Apoptosis inducing protein TRICK2A/2B; Apoptosis inducing receptor TRAIL R2; CD 262; CD262; CD262 antigen; Cytotoxic TRAIL receptor 2; Death domain containing receptor for TRAIL/Apo 2L; Death domain containing receptor for TRAIL/Apo2L; Death receptor 5; DR 5; DR5; Fas like protein precursor; KILLER; KILLER/DR5; OTTHUMP00000123492; OTTHUMP00000123493; p53 regulated DNA damage inducible cell death receptor; killer; p53 regulated DNA damage inducible cell death receptor; killer; TNF related apoptosis inducing ligand receptor 2; TNF related apoptosis inducing ligand receptor 2; TNF-related apoptosis-inducing ligand receptor 2; TNFRSF10B; TR10B_HUMAN; TRAIL R2; TRAIL receptor 2; TRAIL-R2; TRAILR2; TRANCER; TRICK2; TRICK2A; TRICK2B; TRICKB; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor like protein ZTNFR9; Tumor necrosis factor receptor superfamily member 10b; Tumor necrosis factor receptor superfamily, member 10b; ZTNFR9.	WB, ICC/IF	Human, Mouse
	DR5 Antibody (YA5269) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to DR5.

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Cat. No.	Product Name		Classification

HY-174714

Human FAS mRNA		mRNA
Human FAS mRNA encodes the human Fas cell surface death receptor (FAS) protein, a member of the TNF-receptor superfamily. FAS has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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Remarks

Inhibitors & Agonists

Peptides

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Fas receptor

Inhibitors & Agonists

Peptides

NaturalProducts

Recombinant Proteins

Antibodies

Oligonucleotides

Natural
Products