2040964-58-5
Chemical Structure
Xelafaslatide
Synonym(s): ONL-1204
- CAS 番号: 2040964-58-5
- Formula:C71H100N18O16
- Molecular Weight:1461.66
InChIKey: MDQMJABKOUZYGG-QZJYLVOGSA-N
SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N)=O)CC5=CC=C(C=C5)O)=O)=O
Biological Activity: Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma[1].
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Xelafaslatide | 99.88% | Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma. | ||||||||||||||||||||
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