2040964-58-5

Xelafaslatide Chemical Structure
2040964-58-5

Chemical Structure

Xelafaslatide

Synonym(s): ONL-1204

  • CAS No.: 2040964-58-5
  • Formula:C71H100N18O16
  • Molecular Weight:1461.66

InChIKey: MDQMJABKOUZYGG-QZJYLVOGSA-N

SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N)=O)CC5=CC=C(C=C5)O)=O)=O

Biological Activity: Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma[1].

Cat. No. Nom du produit Pureté Description Pricing
HY-P10227 		Xelafaslatide 99.94% Xelafaslatide (ONL-1204) is a Fas receptor antagonist. Xelafaslatide blocks the Fas receptor signaling pathway and inhibits downstream apoptosis and inflammatory pathways. Xelafaslatide suppresses neuroinflammation and microglial activation in glaucoma models, protects retinal ganglion cells and prevents axonal degeneration. Xelafaslatide is applicable to relevant research on glaucoma.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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