2 Results for "

Ferroptosis-IN-8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ferroptosis-IN-8" in MCE Product Catalog:

Cat. No.: HY-163654
CAS No.: 3056016-82-8
Target:  

Ferroptosis

Research Areas:  

Cancer

Ferroptosis-IN-8 is a potent ferroptosis inhibitor with an EC50 of 40.49 nM. Ferroptosis-IN-8 effectively reduces lipid ROS levels in cells. Ferroptosis-IN-8 act as an antioxidant by capturing lipid radicals, leading to a reduction in the accumulation of harmful lipid peroxides and, ultimately, inhibiting ferroptosis .
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Cat. No.: HY-174345
CAS No.: 3097194-74-3
Ferroptosis inducer-8 is a ferroptosis inducer with high selectivity for other cell death mechanism. Ferroptosis inducer-8 induces ferroptosis by affecting ACSL4, GPX4, and FTH1, thereby disrupting intracellular iron homeostasis and the GSH/GPX4 antioxidant defense system, ultimately leading to the accumulation of lipid peroxidation. Ferroptosis inducer-8 also induces ROS production. Ferroptosis inducer-8 inhibits tumor growth and can be used for research of triple-negative breast cancer (TNBC) .
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