1 Result for "

Fumagilin-105

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Fumagilin-105" in MCE Product Catalog:

Cat. No.: HY-161742
CAS No.: 2410081-58-0
Target:  

AUTOTACs MetAP Autophagy p62

Research Areas:  

Cancer

Fumagilin-105 is an autophagy-targeting chimera (AUTOTAC) that degrades MetAP2 via p62-mediated macroautophagy in a ubiquitination-independent manner. Fumagilin-105 can inhibit the migration of tumor cells and induce programmed cell death. Fumagilin-105 has anti-tumor activity. (p62-ZZ ligand (HY-W489121); target-binding ligand (HY-B0751); linker (HY-W245803)) .
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