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Furin-IN-3

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-180145

    Furin Influenza Virus Infection
    Furin-IN-3 (Compound 9) is a potent and selective proprotein convertase furin inhibitor with a Ki of 12.4 nM. Furin-IN-3 shows a Ki of 278 nM for PC7. Furin-IN-3 shows a significant antiviral effect on the Furin-dependent H7N7 influenza A virus strain SC35M. Furin-IN-3 can inhibit the cleavage and activation of the viral hemagglutinin (HA), prevent the fusion of the viral membrane with the host cell membrane, and thereby inhibit viral replication and proliferation. Furin-IN-3 can be used for the research of infection, such as influenza virus infection .
    Furin-IN-3

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