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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
15 Results for "
GPCR19
" in MedChemExpress (MCE) Product Catalog:
Products (15)
15 Results for "GPCR19" in MCE Product Catalog:
39
39 Publications Verification
Research Areas:
SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5 .
30
30 Cited Publications
Synonyms: Ursodeoxycholate; Ursodiol; UDCA
30
30 Cited Publications
Synonyms: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium
6
6
3
Research Areas:
TGR5 Receptor Agonist (CCDC), a potent Takeda G protein-coupled receptor 5 (TGR5; GPCR19) agonist, shows improved potency in the U2-OS cells and melanophore cells with pEC50s of 6.8 and 7.5, respectively. TGR5 Receptor Agonist can induce peripheral and central hypersensitivity to bladder distension in mice, and increase intracellular Ca 2+ concentration. TGR5 Receptor Agonist can also reduces food intake and improves insulin responsiveness, in diet-induced obese mice. TGR5 Receptor Agonist can be used to research diabetes, bladder hypersensitivity and anti-obesity .
Synonyms: Ursodeoxycholate-d4; Ursodiol-d4; UDCA-d4
Synonyms: Ursodeoxycholate (Standard); Ursodiol (Standard); UDCA (Standard)
Cat. No.: HY-RS05622
Target:
Research Areas:
GPBAR1 Human Pre-designed siRNA Set A contains three designed siRNAs for GPBAR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-13771S1
CAS No.: 63296-46-8
Synonyms: Ursodeoxycholate-13C; Ursodiol-13C; UDCA-13C
Cat. No.: HY-14229R
CAS No.: 1197300-24-5
Synonyms: CCDC (Standard)
Research Areas:
TGR5 Receptor Agonist (Standard) is the analytical standard of TGR5 Receptor Agonist. This product is intended for research and analytical applications. TGR5 Receptor Agonist (CCDC), a potent Takeda G protein-coupled receptor 5 (TGR5; GPCR19) agonist, shows improved potency in the U2-OS cells and melanophore cells with pEC50s of 6.8 and 7.5, respectively. TGR5 Receptor Agonist can induce peripheral and central hypersensitivity to bladder distension in mice, and increase intracellular Ca2+ concentration. TGR5 Receptor Agonist can also reduces food intake and improves insulin responsiveness, in diet-induced obese mice. TGR5 Receptor Agonist can be used to research diabetes, bladder hypersensitivity and anti-obesity .
Cat. No.: HY-111534R
CAS No.: 882366-16-7
Research Areas:
SBI-115 (Standard) is the analytical standard of SBI-115 (HY-111534). This product is intended for research and analytical applications. SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5 .
Cat. No.: HY-P704194
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: GPBAR1; Membrane-Type Receptor For Bile Acids; G Protein-Coupled Bile Acid Receptor 1; G-Protein Coupled Receptor GPCR19; M-BAR; MGC40597; BG37; GPCR; TGR5; G-Protein Coupled Bile Acid Receptor BG37; GPCR19; Membrane Bile Acid Receptor; GPR131; HGPCR19; G
Species:
Human
Source:
E. coli Cell-free
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
