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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
Ganglioside GM2
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "Ganglioside GM2" in MCE Product Catalog:
Research Areas:
Ganglioside GM2 is a human tumor antigen predominantly found in human tumor cells and fetal brain tissue. As a sialylated glycosphingolipid, Ganglioside GM2 is involved in processes such as cell signaling, adhesion, and motility. Ganglioside GM2 abnormal expression and accumulation are associated with tumors and neurodegenerative disorders. Ganglioside GM2 promotes tumor cell migration and invasion by directly binding to the integrin β1 receptor, activating the FAK/Src/Erk-MAPK signaling pathway, and inducing actin cytoskeleton remodeling .
Cat. No.: HY-W127461
CAS No.: 35960-33-9
Synonyms: Gangliotriosylceramide
Cat. No.: HY-171942A
Synonyms: C24:1-GM2 ammonium
Target:
Research Areas:
C24:1 Ganglioside GM2 (d18:1/24:1) (ammonium) is an endogenous monosialylated ganglioside. C24:1 Ganglioside GM2 (d18:1/24:1) (ammonium) is a self-lipid that can bind to CD1d in HEK293T cells .
Cat. No.: HY-165676AS
CAS No.: 2750534-90-6
Synonyms: C16 GM2-dN; N-CDN-Palmitoyl-GM2, N-Hexadecaoyl-dN (13,13,14,14,15,15,16,16,16)-Moosialogaglioside GM2; N-Palmitoyl Moosialogaglioside GM2-d9
Cat. No.: HY-171942
CAS No.: 3077081-42-3
Synonyms: C24:1-GM2
Target:
Research Areas:
C24:1 Ganglioside GM2 (d18:1/24:1) (C24:1-GM2) is a monosialylated ganglioside that contains nervonic acid.
Cat. No.: HY-152003S
CAS No.: 2692623-87-1
Cat. No.: HY-E70049
CAS No.: 67338-98-1
Synonyms: GM2/GD2 synthase
Target:
Research Areas:
beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) (GM2/GD2 synthase) is a key enzyme which catalyzes the conversion of GM3, GD3 and lactosylceramide (LacCer) to GM2, GD2 and asialo-GM2 (GA2), respectively. beta-1,4-N-Acetylgalactosaminyltransferase (CgtA) is a key enzyme to control the synthesis of brain-enriched complex gangliosides .
Cat. No.: HY-P991639
Cat. No.: HY-108241A
CAS No.: 1145878-98-3
Target:
Research Areas:
Galacto-PUGNAc is a selective competitive inhibitor of lysosomal β-hexosaminidases (HEX), with Ki values of 51 and 18 nM, for hHEXA and hHEXB, respectively. Galacto-PUGNAc elevates GM2 ganglioside levels in neuroblastoma cells. Galacto-PUGNAc can be used for the research of neurodegenerative disorders .
Cat. No.: HY-N15906
CAS No.: 94458-61-4
Category:
Target:
Cat. No.: HY-P70954
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GM2A; GM2AP; Ganglioside GM2 Activator; GM2 Ganglioside Activator; GM2-AP; GM2-Activator Protein; SAP-3; GM2 Ganglioside Activator Protein; Cerebroside Sulfate Activator Protein; Shingolipid Activator Protein 3; Sphingolipid Activator Protein 3; Alternati
Species:
Human
Source:
HEK293
Cat. No.: HY-P75160
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GM2A; GM2AP; Ganglioside GM2 Activator; GM2 Ganglioside Activator; GM2-AP; GM2-Activator Protein; SAP-3; GM2 Ganglioside Activator Protein; Cerebroside Sulfate Activator Protein; Shingolipid Activator Protein 3; Sphingolipid Activator Protein 3; Alternati
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
