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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
HBsAg secretion
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "HBsAg secretion" in MCE Product Catalog:
Category:
Flavonoids Thymelaeaceae Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology Biflavones Stellera chamaejasme L.
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Cat. No.: HY-N4168
CAS No.: 123483-19-2
Category:
other families Simple Phenylpropanols Other Diseases Phenols Polyphenols Phenylpropanoids Plants Disease Research Fields
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Category:
Infection Lignans Phenylpropanoids Plants Schisandraceae Disease Research Fields Schisandra chinensis (Turcz.) Baill.
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HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis .
Cat. No.: HY-162579
CAS No.: 3036114-68-5
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TLR7 agonist 22 (Compound 11a) emerges as a selective TLR7 agonist with an IC50 value of 25.86 μM. TLR7 agonist 22 inhibits the cellular HBsAg secretion and effectively activates TLR7, thereby inducing the secretion of TLR7-regulated cytokines IL-12, TNF-αand IFN-αin human PBMC cells. TLR7 agonist 22 is a promising for research in the field of developing novel immunomodulatory anti-HBV agents .
Cat. No.: HY-N3093
CAS No.: 1025023-05-5
Synonyms: (+)-Periglaucine B
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Cat. No.: HY-P2783
CAS No.: 79386-00-8
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Cat. No.: HY-W754691
CAS No.: 6808-72-6
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Cat. No.: HY-145053A
CAS No.: 2716907-15-0
(5S,8R)-HBV-IN-10 is an enantiomer of compound 6 (WO2021204258A1). Compound 6 is a hepatitis B surface antigen (HBsAg) inhibitor (0.001 μM< EC50 ≤0.05 μM). From patent WO2021204258A1, compound 6 .
Cat. No.: HY-170605
BA-AZT1 is the inhibitor for HBV polymerase and sodium taurocholate cotransporting polypeptide (NTCP). BA-AZT1 inhibits the secretion of viral capsid protein HBsAg and HBeAg with IC50 of 0.65 µM and 13.42 µM, inhibits the HBV DNA replication with an IC50 of 0.70 µM .
Cat. No.: HY-N3094
CAS No.: 1025023-04-4
Cat. No.: HY-107315
CAS No.: 443683-76-9
Cat. No.: HY-N11792
CAS No.: 1283600-08-7
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Cat. No.: HY-176059
HBV-IN-52 is a selective HBV inhibitor. HBV-IN-52 is a Neplanocin A (HY-130430) derivative that demonstrates significant activity against HBV replication with EC50 = 0.96 μM. HBV-IN-52 can inhibit HBsAg secretion (EC50 = 0.82 μM. HBV-IN-52 can be studied in research for chronic hepatitis B (CHB) infections .
Cat. No.: HY-N12105
CAS No.: 1015175-06-0
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Cat. No.: HY-134635R
CAS No.: 1080-12-2
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Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
